Role of Cardiac MRI in Complicated Cardiac Defects

Insights into role of microRNAs in cardiac development, cardiac diseases, and developing novel therapies

Objective(s): MicroRNAs (miRNAs) are a subfamily of small noncoding RNAs that play a variety of roles in regulating gene expression in nearly all organisms. They affect different biological pathways by post-transcriptionally regulating mRNAs. Aside from miRNAs’  role in maintaining cellular homeostasis, their perturbation is related to several pathologic states and dis...

Cardiac MRI

Introduction Cardiac MR imaging allows for the examination of anatomy, function, and metabolism and its clinical use is steadily increasing. It poses unique challenges to the imaging protocols as it requires high spatial resolution over a larger volume in the presence of cardiac and breathing motion. This overview of cardiac MRI discusses methods to reduce motion artifacts and various clinical ...

Role of cardiac MRI and CT in Fontan circulation

A Fontan circulation is a series of palliative surgical procedures, which result in the diversion of the systemic venous return into pulmonary arterial circulation without passing through a ventricle. It is one of the available surgical strategies for patients with cardiac defects that preclude a successful bi-ventricular repair, which encompass a range of complex anatomy. This surgical repair ...

cardiac ct in mixed type atrial septum defects

Cardiac MRI at 7T

In the brain, results have been shown at 7T that are not achievable at lower field strengths. Cardiac imaging at 7T offers similar headline benefits to those images of the brain. More field strength gives more SNR, added to which more field strength increases the T1 and hence increases the effect of contrast agents. This simple idea is appealing in a grant application, but in reality 7T has som...